The Equine Disease Communication Center (EDCC) has reported, and the Florida Department of Health has confirmed, a case of equine rabies in Madison County, Florida. It’s the state’s first reported equine rabies case of 2016.

According to the EDCC, the premises and one remaining exposed horse with no previous rabies vaccine history have been placed under quarantine.

Rabies is a fatal neurologic disease that affects all mammals. The American Association of Equine Practitioners recommends rabies as one of four core vaccines every horse should receive.