Horses Needed for Metabolic Syndrome and Laminitis Research

The equine genetics research group at the University of Minnesota College of Veterinary Medicine is collaborating with Dr. Ray Geor, professor and chair of the department of large animal clinical sciences at Michigan State University, and Dr. Nicholas Frank, associate professor of large animal clinical sciences at the University of Tennessee, to investigate the occurrence and genetics of equine metabolic syndrome (EMS).
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The equine genetics research group at the University of Minnesota College of Veterinary Medicine is collaborating with Ray Geor, BVSc, MVSc, PhD, Dipl. ACVIM, professor and chair of the department of large animal clinical sciences at Michigan State University, and Nicholas Frank, DVM, PhD, Dipl. ACVIM, associate professor of large animal clinical sciences at the University of Tennessee, to investigate the occurrence and genetics of equine metabolic syndrome (EMS). Bob Coleman, PhD, PAS, associate director for undergraduate education in equine science and management and extension horse specialist at the University of Kentucky also is involved in the study.

EMS is a condition characterized by obesity and/or regional adiposity (cresty neck), elevation of blood insulin levels, and increased risk for laminitis development. Certain horses that seem predisposed to EMS often are referred to as “easy keepers.” These horses are very efficient at utilizing calories and often require a lower plane of nutrition to maintain body weight than other horses. This difference in EMS susceptibility among horses managed under similar conditions is likely the result of a genetic predisposition.

The goal of this investigation is to better understand the role of breed, gender, age, environment (diet and exercise), and genetics in EMS. The success of the study depends on the collection of data from as many horses with EMS as possible; therefore, horse owner and veterinarian assistance is critical.

Thus far, more than 500 horse owners have provided information about their horses, which has already helped increase the research team’s understanding of EMS and laminitis. However, to meet all of the team’s research goals, they need many more horse owners’ help. The researchers’ aim is to identify genetic markers that will predict a horse’s risk level for developing EMS and laminitis before clinical signs manifest, allowing owners and veterinarians to initiate management practices that better protect their horses from developing disease

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