Tying Up is Split Up

Muscle disease in performance horses commonly is referred to as tying-up, exertional rhabdomyolysis, azoturia, or Monday morning disease. Horses experiencing tying-up show a stiff gait; reluctance to move; firm, painful muscle cramps; profuse sweating; increased heart rate; and increased respiratory rate. Horses that tie up also have moderate to marked elevations of certain muscle proteins in

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