Mare Reproductive Health Gets Help From Newly FDA-Approved Drug

After years of intensive research, a product called SucroMate has achieved the coveted status of FDA-approved for reproductive health in mares. This is no easy feat as only two veterinary drugs obtained FDA approval in 2010. SucroMate is licensed to induce ovulation in mares being bred with fresh, cooled, or frozen semen.
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After years of intensive research, a product called SucroMate has achieved the coveted status of FDA-approved for reproductive health in mares. This is no easy feat as only two veterinary drugs obtained FDA approval in 2010. SucroMate is licensed to induce ovulation in mares being bred with fresh, cooled, or frozen semen.

"SucroMate contains a drug called deslorelin acetate," explained Edward Squires, PhD, a specialist in equine reproduction at the University of Kentucky's Gluck Equine Research Center. "It is administered intramuscularly once the mare has a egg-containing follicle on her ovary measuring 35 mm in diameter or larger, is in estrus, and has a open cervix. Ovulation should occur within 48 hours of administration."

Squires played a key role in the development and testing of this product.

"I did a study at Colorado State University that was centered on determining the safety and efficacy of the product," said Squires. "We found that this drug is very safe. After (testing the drug by) administering (up to five times) the regular dose, no serious side effects were noted." Only a small number of mares had a slight swelling at the injection site, he added

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Written by:

Stacey Oke, MSc, DVM, is a practicing veterinarian and freelance medical writer and editor. She is interested in both large and small animals, as well as complementary and alternative medicine. Since 2005, she’s worked as a research consultant for nutritional supplement companies, assisted physicians and veterinarians in publishing research articles and textbooks, and written for a number of educational magazines and websites.

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