Exertional Rhabdomyolysis (tying-up)
News/Interview
Tying Up Explained
Dr. Erica McKenzie describes the common causes of exertional rhabdomyolysis in horses.
Article
Exertional Rhabdomyolysis: Not Just Tying-Up Anymore
Researchers have worked tirelessly to better understand the disorder, its causes, and how to best manage it.
Photo by Stephanie Valberg, DVM, PhD
Article
Top Medicine Studies of 2012 (AAEP 2012)
Dr. Stephen Reed recaps studies on endocrinology, neurologic and muscle disorders, foal health, and more.
Photo by Photos.com
Video
Tying Up Explained
May 21, 2013
Dr. Erica McKenzie describes the common causes of exertional rhabdomyolysis in horses.... Read More
Video
Red Urine Risk After Tying Up Episode
May 17, 2013
Dr. Erica McKenzie shares why red urine is a concern in horses that are tying up.... Read More
Video
Rest is Recommended When a Horse Ties Up
May 15, 2013
Dr. Erica McKenzie answers a common question. Should a horse walk or rest when tying up?... Read More
Article
Old School Tying Up Treatment
May 14, 2013
Why have vitamin E/selenium injections prior to whatever led to tying-up in the past been abandoned?... Read More
Download
2012 Frank J. Milne State-of-the-Art Lecture
March 20, 2013
Dr. Stephanie Valberg discussed exertional rhabdomyolysis (formerly tying up) at the 2012 Milne lecture.... Read More
Article
Exertional Rhabdomyolysis: Not Just Tying-Up Anymore
February 12, 2013
Researchers have worked tirelessly to better understand the disorder, its causes, and how to best manage it.... Read More
Article
Top Medicine Studies of 2012 (AAEP 2012)
February 04, 2013
Dr. Stephen Reed recaps studies on endocrinology, neurologic and muscle disorders, foal health, and more.... Read More
Article
Valberg to be Inducted into Equine Research Hall of Fame
September 16, 2012
Valberg will be the first woman inducted into the Equine Research Hall of Fame.... Read More
Article
Identifying and Managing Acute Rhabdomyolysis in Horses
July 25, 2012
Understanding equine acute rhabdomyolysis can help ensure affected horses receive appropriate veterinary care.... Read More
Article
Exertional Muscle Disorders Topic of 2012 Milne Lecture
June 05, 2012
Stephanie Valberg, DVM, PhD, is the first female to deliver the Milne State-of-the-Art Lecture.... Read More
Article
Selenium and Vitamin E to Alleviate Signs of Tying Up
May 20, 2012
Selenium and vitamin E work together to alleviate muscle damage and signs of tying up in horses.... Read More
Article
Tying-Up in Horses: A Review
June 15, 2011
Tying-up, or exertional rhabdomyolysis, is a frustrating problem for horse owners, but can be managed through ... Read More
Article
What's In Your Horse's DNA?
December 01, 2010
Geneticists have created tools and tests that enhance horse breeders' ability to select for healthy foals.... Read More
Article
Neuromuscular Disease Can Lead to Performance Issues
October 24, 2010
Neuromuscular diseases, which affect the function of muscles and the way they interact with the nervous system, can lead to performance issues, said Kelsey A. Hart, DVM, PhD, Dipl. ACVIM, internal medicine clinician and graduate fellow at the U... Read More
Article
Potential Biomarker for Tying-up Found
June 01, 2010
In an equine study using "proteomic" technology that systematically analyzed the proteins in skeletal muscle biopsies, a research team from The Netherlands identified a form of the protein creatine kinase that could be a marker for ac... Read More
Article
Twelve New Equine Fact Sheets Available From TheHorse.com
May 12, 2010
This week TheHorse.com has launched 12 free, handy Fact Sheets on topics of interest to hands-on horse owners. These are invaluable additions to the more than 30 widely acclaimed Fact Sheets that TheHorse.com launched in 2009...... Read More
Article
Nutrition Can Help Manage Tying-Up in Sport Horses
May 10, 2010
Thanks to advances in identifying specific causes of tying-up, development of diagnostic tests, and improved recognition of the impact of diet and exercise on horses that tie up, affected horses can be successfully managed. Stephanie Valberg, D... Read More
Download
Tying-up in Horses
May 01, 2010
Tying-up, also known as azoturia, set fast, or Monday morning disease, is a common equine muscle disease.... Read More
Article
Genetic Diseases in Horses Reviewed for World Equine Vets
October 31, 2009
While genetic diseases exist in a number of horse breeds, many researchers have focused expressly on issues occurring in the Quarter Horse breed. Thanks to their efforts, genetic tests for several disorders specific to this breed are now... Read More
Article
PSSM Genetic Mutation Reported in Some UK Horse Breeds
June 18, 2009
Collaborative efforts between researchers on both sides of the Atlantic have identified that a genetic mutation in enzyme glycogen synthase 1 (GYS1) is an important cause of polysaccharide storage myopathy (PSSM, a form of... Read More
Article
UK Incidence of Polysaccharide Storage Myopathy Reported
May 21, 2009
Not only is polysaccharide storage myopathy (PSSM) a common and important muscular disorder in various horse breeds in the United States, but according to a recent research report, it is also a common diagnosis in horses in the Unite... Read More
Article
Muscle Disorders in Warmbloods Easily Diagnosed through Biopsy
April 16, 2008
Owners of Warmbloods with debilitating--or sometimes just plain baffling--muscle disorders can get useful and reliable answers about their horses' conditions through a relatively simple muscle biopsy. So say University of Minnesota researchers,... Read More
Article
Polysaccharide Storage Myopathy: Blame It on the Genes
April 11, 2008
A genetic mutation in an enzyme called muscle glycogen synthase might be responsible for polysaccharide storage myopathy (PSSM)--a debilitating and life-threatening disease in horses characterized by abnormally high glycogen (the storage form of... Read More
Article
Service Pony Recovers from Health Crisis
April 10, 2008
Thanks to the skill and kindness of several Texas veterinarians, a blind woman's assistive guide pony is recuperating from serious illness. Trixie is a nearly 14-year-old Pony of the Americas mare, and she has been Tabitha Darling's service... Read More
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Farm Call: Your Questions Answered
Old School Tying Up Treatment
Q. Your article on tying-up left out the old remedy I have used successfully every time: vitamin E/selenium injections prior to whatever led to tying-up episodes in the past. I never had this fail and wonder why it has been abandoned?
Tying-Up Syndrome
Q. I just bought a Thoroughbred filly which was in race training, but retired without running because of recurrent bouts of ‘tying-up.’ She had been turned out for six months before I got her, and never showed any problems while on the farm. What can you tell me about this disease? Tying-up is a syndrome or description of a horse with muscle damage that has many different causes
