Recent News for Metabolic Problems

Article

Diagnosing Pituitary Pars Intermedia Dysfunction

July 17, 2007

Unfortunately, no perfect PPID test (one that is 100% accurate with a single-sample test) yet exists. At the 2006 AAEP Convention, Harold Schott, DVM, PhD, Dipl. ACVIM, professor of large animal clinical sciences at Michigan State University,... Read More

Article

Glycogen-Branching Enzyme Deficiency (AAEP 2006)

July 16, 2007

Glycogen-branching enzyme deficiency, a genetic mutation affecting a particular glycogen-storage enzyme, is traced back to Quarter Horse sire King or his sire, Zantanon. Up to 8% of Quarter Horses and Paint horses carry the GBED defect. ... Read More

Article

Insulin Resistance: Hold the Grain, Please

July 12, 2007

Management of insulin resistance might lower the risk of laminitis, and one of the cornerstones of management is diet. “Think of these horses as being in a prediabetic state,” said Nicholas Frank, DVM, PhD, Dipl. ACVIM, associate professor of... Read More

Article

Polysaccharide Storage Myopathy

July 09, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center discussed PSSM at the AAEP Convention 2006. The disorder causes muscle pain, stiffness, and cramping, and some horses... Read More

Article

Diagnostic Approach To Equine Muscle Disorders

July 07, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, began the in-depth seminar on muscle disorders by discussing diagnosis of muscle disorders, beginning with a careful... Read More

Article

Hyperkalemic Periodic Paralysis: 14 Years Later

July 04, 2007

Sharon Spier, DVM, Dipl. ACVIM, PhD, associate professor at the University of California, Davis, has pioneered much of the research on HYPP. She presented updated information gleaned over the past 14 years on this disease at the 2006 AAEP... Read More

Article

Incidence and Management of Exertional Rhabdomyolysis

July 03, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, tackled the broad subject of skeletal muscle disease related to exercise at the 2006 AAEP Convention.

This has... Read More

Article

Challenges of Cushing's Disease Diagnosis and Treatment

July 02, 2007

We know Cushing's disease (or pituitary pars intermedia dysfunction—PPID—as it's more scientifically called), simply put, is an "old-horse disease" that results in metabolism disturbances and an abnormally heavy hair coat. But when it comes to... Read More

Article

Polysaccharide Storage Myopathy Discussion Planned at SmartPak Store

June 14, 2007

Most horse owners are familiar with the term "tying up," which describes the pain and cramping of a horse's muscles with exercise. Veterinarians refer to this condition as exertional rhabdomyolysis, and now recognize a specific type known as... Read More

Article

Finding and Testing Low-Sugar Forage

May 14, 2007

Did the brown, stemmy, overmature hay you thought was perfect for your easy keepers make them even fatter? ... Read More

Article

Pergolide: FDA to Allow Compounding From Bulk

May 11, 2007

The Food and Drug Administration's (FDA) Center for Veterinary Medicine announced on May 11 it will allow bulk pergolide to be used in compounding pergolide for use in horses.

Pergolide mesylate, a drug commonly used to treat pituitar... Read More

Article

Pergolide Availability: No FDA Announcement, Supplies Running Low

May 04, 2007

More than a month after pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, was withdrawn for human use, the FDA has yet to make an announcement on whether... Read More

Article

Pergolide: Veterinarians, Horse Owners Fighting for Availability

April 17, 2007

Pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, has been withdrawn for human use. The FDA made this announcement March 29. Since that time, horse owners and... Read More

Article

Equine Cushing's Drug Pergolide to be Withdrawn for Human Use

April 04, 2007

The FDA has announced pergolide is to be voluntarily withdrawn for human use. Pergolide is commonly used for horses with pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease.

According to the FDA announcement... Read More

Article

AAEP Convention 2006: Obese Horses

March 01, 2007

Adipobiology (The Study of Fat in the Body): An Emerging Field... Read More

Article

Muscle Disorders (AAEP 2006)

March 01, 2007

Careful inspection of a horse's muscle mass and symmetry and hands-on palpation educates the examiner about the horse's muscle tone and comfort level. The examiner also evaluates the horse in motion and conducts a full lameness exam.... Read More

Article

Nutrition to Go

March 01, 2007

A group of veterinarians gathered at the Land O' Lakes Purina Mills headquarters in St. Louis, Mo., last fall to participate in discussions on subjects that ranged from Cushing's disease to proper nutrition for horses young and old. Nicholas Frank,... Read More

Article

Equine Metabolic Syndrome Versus Cushing's Syndrome

February 19, 2007

Fresh from the AAEP Annual Convention, here's an update on what we know about these two disorders and how to manage them:

Equine metabolic syndrome typically affects horses aged 8 to 18-years-old. Pony breeds, domesticated Spanish... Read More

Article

Dopamine and Its Evil Twin Ergovaline

February 01, 2007

In the horse, the hormone dopamine exerts a number of effects through its actions on the pituitary gland. Both dopamine and ergovaline, a dopaminergic agonist (a drug that stimulates dopamine receptors), can significantly impact the mare's... Read More

Article

Prevalence of PSSM in Quarter Horses

September 14, 2006

Up to 6% of apparently healthy Quarter Horses could have subclinical polysaccharide storage myopathy (PSSM).... Read More

Article

Feeding to Prevent and Control Disease

August 01, 2006

Dietary management can work like magic for specific equine diseases.... Read More

Article

Cushing's Disease in Horses

March 01, 2006

It's spring, yet your aging equine has failed to shed his long, shaggy, winter coat. Furthermore, he's developed a saggy belly coupled with loss of muscle over his croup and rump. He's gulping down far more water than he used to, and his stall i... Read More

Article

Inheritance of RER in Thoroughbreds: One Affected Parent Required

January 01, 2006

Recurrent exertional rhabdomyolysis (RER, tying-up) causes affected Thoroughbreds to suffer recurring episodes of muscle cramping, stiffness, excessive sweating, and a reluctance to move after exercise. With no cure available, information on how... Read More

Article

Inheritance of RER in Thoroughbreds

November 21, 2005

Recurrent exertional rhabdomyolysis (RER) causes affected Thoroughbreds to suffer recurring episodes of muscle cramping, stiffness, excessive sweating, and a reluctance to move after exercise. With no cure available, information on how RER might... Read More

Article

Equine Genetic Disease: Who's At Risk?

October 01, 2005

Many DNA sequence variations are fine; they just give rise to the broad spectrum of colors, sizes, and other characteristics we see in the horse population. Some variations, however, cause problems. These might range from a genetic predisposition... Read More