Recent News for Metabolic Problems

Article

Healthy Horses: Endocrine System Function and Flaws

September 25, 2007

Horses suffer from few endocrine disorders compared to humans and companion animals; however, they're not totally off the hook, explained Emily Graves, VMD, MS, Dipl. ACVIM, of Michigan State University, to horse owners in attendance at the... Read More

Article

Managing Hyperkalemic Periodic Paralysis

August 08, 2007

At the 2006 American Association of Equine Practitioners Convention, Dr. Sharon Spier spoke about HYPP.... Read More

Article

The Role of Obesity in Insulin Resistance

August 04, 2007

"Not all obese individuals are insulin-resistant, and not all IR-affected horses are obese. But IR-associated medical problems are more likely to develop in concert with obesity in individuals born with IR," said Nat Messer, DVM, Dipl. ABVP, an... Read More

Article

Obesity, Insulin Resistance, and Laminitis

July 31, 2007

Insulin resistance is a part of equine metabolic syndrome (EMS). There are three criteria for identifying the horse with EMS: Insulin resistance, prior (founder lines) or current laminitis, and general obesity or regional adiposity (areas of abnormal... Read More

Article

What Causes Pituitary Pars Intermedia Dysfunction?

July 23, 2007

The lack of dopamine is critical, as the activity of the pars intermedia is normally inhibited (controlled) by dopamine. Without dopamine, the pars intermedia produces much more hormone than it should, causing the clinical signs of PPID.... Read More

Article

Treating Pituitary Pars Intermedia Dysfunction (or Cushing's Disease)

July 19, 2007

Medication options for PPID include pergolide, cyproheptadine, trilostane, and chasteberry extract. One disadvantage is that no treatment is currently FDA-approved for PPID in horses.... Read More

Article

Understanding Pituitary Pars Intermedia Dysfunction (a.k.a. Cushing's Disease)

July 18, 2007

Pituitary pars intermedia dysfunction--PPID, or Cushing's disease--is the most common disease of horses and ponies 15 years of age or older. Although it's not fully understood yet, researchers are learning more about how to treat and prevent it.... Read More

Article

Diagnosing Pituitary Pars Intermedia Dysfunction

July 17, 2007

Unfortunately, no perfect PPID test (one that is 100% accurate with a single-sample test) yet exists. At the 2006 AAEP Convention, Harold Schott, DVM, PhD, Dipl. ACVIM, professor of large animal clinical sciences at Michigan State University,... Read More

Article

Glycogen-Branching Enzyme Deficiency (AAEP 2006)

July 16, 2007

Glycogen-branching enzyme deficiency, a genetic mutation affecting a particular glycogen-storage enzyme, is traced back to Quarter Horse sire King or his sire, Zantanon. Up to 8% of Quarter Horses and Paint horses carry the GBED defect. ... Read More

Article

Insulin Resistance: Hold the Grain, Please

July 12, 2007

Management of insulin resistance might lower the risk of laminitis, and one of the cornerstones of management is diet. “Think of these horses as being in a prediabetic state,” said Nicholas Frank, DVM, PhD, Dipl. ACVIM, associate professor of... Read More

Article

Polysaccharide Storage Myopathy

July 09, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center discussed PSSM at the AAEP Convention 2006. The disorder causes muscle pain, stiffness, and cramping, and some horses... Read More

Article

Diagnostic Approach To Equine Muscle Disorders

July 07, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, began the in-depth seminar on muscle disorders by discussing diagnosis of muscle disorders, beginning with a careful... Read More

Article

Hyperkalemic Periodic Paralysis: 14 Years Later

July 04, 2007

Sharon Spier, DVM, Dipl. ACVIM, PhD, associate professor at the University of California, Davis, has pioneered much of the research on HYPP. She presented updated information gleaned over the past 14 years on this disease at the 2006 AAEP... Read More

Article

Incidence and Management of Exertional Rhabdomyolysis

July 03, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, tackled the broad subject of skeletal muscle disease related to exercise at the 2006 AAEP Convention.

This has... Read More

Article

Challenges of Cushing's Disease Diagnosis and Treatment

July 02, 2007

We know Cushing's disease (or pituitary pars intermedia dysfunction—PPID—as it's more scientifically called), simply put, is an "old-horse disease" that results in metabolism disturbances and an abnormally heavy hair coat. But when it comes to... Read More

Article

Polysaccharide Storage Myopathy Discussion Planned at SmartPak Store

June 14, 2007

Most horse owners are familiar with the term "tying up," which describes the pain and cramping of a horse's muscles with exercise. Veterinarians refer to this condition as exertional rhabdomyolysis, and now recognize a specific type known as... Read More

Article

Finding and Testing Low-Sugar Forage

May 14, 2007

Did the brown, stemmy, overmature hay you thought was perfect for your easy keepers make them even fatter? ... Read More

Article

Pergolide: FDA to Allow Compounding From Bulk

May 11, 2007

The Food and Drug Administration's (FDA) Center for Veterinary Medicine announced on May 11 it will allow bulk pergolide to be used in compounding pergolide for use in horses.

Pergolide mesylate, a drug commonly used to treat pituitar... Read More

Article

Pergolide Availability: No FDA Announcement, Supplies Running Low

May 04, 2007

More than a month after pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, was withdrawn for human use, the FDA has yet to make an announcement on whether... Read More

Article

Pergolide: Veterinarians, Horse Owners Fighting for Availability

April 17, 2007

Pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, has been withdrawn for human use. The FDA made this announcement March 29. Since that time, horse owners and... Read More

Article

Equine Cushing's Drug Pergolide to be Withdrawn for Human Use

April 04, 2007

The FDA has announced pergolide is to be voluntarily withdrawn for human use. Pergolide is commonly used for horses with pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease.

According to the FDA announcement... Read More

Article

AAEP Convention 2006: Obese Horses

March 01, 2007

Adipobiology (The Study of Fat in the Body): An Emerging Field... Read More

Article

Muscle Disorders (AAEP 2006)

March 01, 2007

Careful inspection of a horse's muscle mass and symmetry and hands-on palpation educates the examiner about the horse's muscle tone and comfort level. The examiner also evaluates the horse in motion and conducts a full lameness exam.... Read More

Article

Nutrition to Go

March 01, 2007

A group of veterinarians gathered at the Land O' Lakes Purina Mills headquarters in St. Louis, Mo., last fall to participate in discussions on subjects that ranged from Cushing's disease to proper nutrition for horses young and old. Nicholas Frank,... Read More

Article

Equine Metabolic Syndrome Versus Cushing's Syndrome

February 19, 2007

Fresh from the AAEP Annual Convention, here's an update on what we know about these two disorders and how to manage them:

Equine metabolic syndrome typically affects horses aged 8 to 18-years-old. Pony breeds, domesticated Spanish... Read More