Recent News for Genetic Problems

Article

Inheritance of RER in Thoroughbreds

November 21, 2005

Recurrent exertional rhabdomyolysis (RER) causes affected Thoroughbreds to suffer recurring episodes of muscle cramping, stiffness, excessive sweating, and a reluctance to move after exercise. With no cure available, information on how RER might... Read More

Article

Equine Genetic Disease: Who's At Risk?

October 01, 2005

Many DNA sequence variations are fine; they just give rise to the broad spectrum of colors, sizes, and other characteristics we see in the horse population. Some variations, however, cause problems. These might range from a genetic predisposition... Read More

Article

GBED Linked to Quarter Horse Bloodlines

March 29, 2005

Glycogen-branching enzyme disorder (GBED) has likely been a cause of neonatal mortality in Quarter Horses for decades, according to Stephanie Valberg, DVM, PhD, who gave an update on her research on the disorder at the recent conference of the... Read More

Article

AAEP Convention 2004 Wrap-Up: Medicine/Treatments

March 03, 2005

Equine Malignant Hyperthermia

We've all heard of people and animals that are "sensitive" to anesthesia. Monica Aleman, MVZ, PhD, Dipl. ACVIM, head of the neuromuscular disease lab at the University of California, Davis, reported on a... Read More

Article

Newborn Foals: Routine and Emergency Care

February 14, 2005

The best chance to improve the survival rate of a newborn foal, she said, is adequate advance disease prevention and planning. The disease prevention includes a comprehensive vaccination program, Zimmel told her listeners.... Read More

Article

HC/HERDA Research

February 13, 2005

In horses with HC, the skin separates between the deep and superficial dermis. There is no cure. A DNA test for carrier identification is not yet available, and therefore, managed breeding strategy is currently the only option for reducing the incide... Read More

Article

Medicinal Control of Tying-Up

December 01, 2004

Dantrolene sodium (Dantrium) is used to control exertional rhabdomyolysis (ER, also called tying-up) in horses. Diagnosis of ER is typically confirmed by a finding of increased serum creatine kinase (CK), which is often greater than 1,000 IU at... Read More

Article

Hyperkalemic Periodic Paralysis and Colic

September 01, 2004

Q: I have a 4-year-old Quarter Horse gelding who is HYPP N/H positive. This horse is very gassy and tends to colic once a month, which causes a minor HYPP attack. I have tried everything, from changing his diet (no grain) to jus... Read More

Article

Good/Bad Effects of Antioxidants

July 01, 2004

In a society that is trying to slow the aging process, free radicals and antioxidants are terms that are regularly tossed around. One might not realize their importance in horses, but researchers continue to pursue the details of how and why the... Read More

Article

Fatal Genetic Quarter Horse Disease Identified

June 09, 2004

Glycogen branching enzyme deficiency in Quarter Horses might cause unexplained stillbirths/deaths of foals.... Read More

Article

HC/HERDA Update; Owners of Carrier Stallions Notified

May 17, 2004

Approximately 100 Quarter Horse stallion owners have received, or will receive, a message that the stallion is a carrier of the recessive gene that causes HC, also known as hereditary equine regional dermal asthenia (HERDA).... Read More

Article

Feeding HYPP Horses

May 01, 2004

Hyperkalemic periodic paralysis (HYPP) horses need careful dietary management to reduce attacks.... Read More

Article

HC/HERDA In the News

May 01, 2004

I'm amazed at some of the angry reactions that followed our publication of a news item last month on a hereditary disease called hyperelosis cutis (HC) or hereditary equine regional dermal asthenia (HERDA). Some of the researchers involved--Ann... Read More

Article

HERDA: Not Just Skin Deep

April 01, 2004

Today, it is primarily through Poco Bueno's bloodline that the recessive gene that causes hyperelastosis cutis (HC) has passed. In some scientific circles, the disease is called hereditary equine regional dermal asthenia (HERDA).... Read More

Article

Diet: When Horses Need Less Carbs

April 01, 2004

Research suggests some horses (growing foals, laminitic horses, etc.) could do well on low-glycemic diets. ... Read More

Article

Fever of Unknown Origin in the Foal

March 11, 2004

"Take an organized approach to elucidate causes of fever of unknown origin in the foal," said Robert Franklin, DVM, Dipl. ACVIM, of Goulburn Valley Equine Hospital in Victoria, Australia, during the Western Veterinary Conference held February... Read More

Article

AQHA Board of Directors Votes on Key Rule Changes at Convention

March 11, 2004

The American Quarter Horse Association Board of Directors voted Tuesday on the recommendations of the AQHA standing committees as approved in the general membership meeting. The following is the final results of the vote regarding hyperkalemic... Read More

Article

AQHA Statement on HC/HERDA

March 08, 2004

The American Quarter Horse Association's (AQHA) statement regarding hyperelastosis cutis (HC) or hereditary equine regional dermal asthenia (HERDA): 

1. AQHA is aware of the condition known as hereditary equine regional... Read More

Article

Inherited Quarter Horse Disease Traces To Poco Bueno

February 26, 2004

Poco Bueno was identified as the sire line associated with hereditary equine regional dermal asthenia (HERDA).... Read More

Article

Hereditary Disease Research Into HERDA

February 26, 2004

If we have any doubt about a horse with lesions that look like HERDA (also called HC), we can test to see if that animal does have this disease. Usually it's easy to diagnose, once you've seen a few.... Read More

Article

The Future of Horses with HYPP

December 30, 2003

Letter to the Editor:

This letter must begin by saying how proud I am of a man whom I have never met.  His name is Steve Stevens of Houston, TX, the current president of the American Quarter Horse Association (AQHA).  Mr.... Read More

Article

Dietary Clues to Tying-Up

June 20, 2003

Recurrent exertional rhabdomyolysis (RER, a type of tying-up) is an inherited disorder in Thoroughbreds. Research suggests that RER involves an abnormality in the regulation of calcium in muscle cells. High-grain diets have been implicated as... Read More

Article

Speed Limit

March 05, 2003

The racing Thoroughbred is trapped between a rock and a hard place. The rock is speed, which evolved slowly by natural selection for 50 million years, then rapidly by human hand the last 500. The hard place is where we find our ward today, beset... Read More

Article

When Your Horse's Muscles Ache

March 01, 2003

Equine muscle injuries are often elusive, leading to frustration for the rider and a challenging diagnosis. ... Read More

Article

Diagnosis and Treatment of Rhabdomyolysis in Foals

February 13, 2003

We hear a lot about a horse experiencing rhabdomyolysis (tying-up) during or after exercise. However, foals are also susceptible to muscle damage. Stephanie Valberg, DVM, PhD, of the University of Minnesota, presented "A Review of the Diagnosis... Read More