Recent News for Genetic Problems

Article

Glycogen-Branching Enzyme Deficiency (AAEP 2006)

July 16, 2007

Glycogen-branching enzyme deficiency, a genetic mutation affecting a particular glycogen-storage enzyme, is traced back to Quarter Horse sire King or his sire, Zantanon. Up to 8% of Quarter Horses and Paint horses carry the GBED defect. ... Read More

Article

Polysaccharide Storage Myopathy

July 09, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center discussed PSSM at the AAEP Convention 2006. The disorder causes muscle pain, stiffness, and cramping, and some horses... Read More

Article

Diagnostic Approach To Equine Muscle Disorders

July 07, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, began the in-depth seminar on muscle disorders by discussing diagnosis of muscle disorders, beginning with a careful... Read More

Article

Hyperkalemic Periodic Paralysis: 14 Years Later

July 04, 2007

Sharon Spier, DVM, Dipl. ACVIM, PhD, associate professor at the University of California, Davis, has pioneered much of the research on HYPP. She presented updated information gleaned over the past 14 years on this disease at the 2006 AAEP... Read More

Article

Incidence and Management of Exertional Rhabdomyolysis

July 03, 2007

Stephanie Valberg, DVM, PhD, professor of large animal medicine and director of the University of Minnesota's Equine Center, tackled the broad subject of skeletal muscle disease related to exercise at the 2006 AAEP Convention.

This has... Read More

Article

Polysaccharide Storage Myopathy Discussion Planned at SmartPak Store

June 14, 2007

Most horse owners are familiar with the term "tying up," which describes the pain and cramping of a horse's muscles with exercise. Veterinarians refer to this condition as exertional rhabdomyolysis, and now recognize a specific type known as... Read More

Article

HERDA: DNA Tests Available for Disfiguring Skin Disease

May 28, 2007

Scientific research has scored another significant victory in the equine world. Two DNA tests are now available to detect carrier status for hereditary equine regional dermal asthenia (HERDA), also known as hyperelastosis cutis (HC).

Today... Read More

Article

Finding and Testing Low-Sugar Forage

May 14, 2007

Did the brown, stemmy, overmature hay you thought was perfect for your easy keepers make them even fatter? ... Read More

Article

Muscle Disorders (AAEP 2006)

March 01, 2007

Careful inspection of a horse's muscle mass and symmetry and hands-on palpation educates the examiner about the horse's muscle tone and comfort level. The examiner also evaluates the horse in motion and conducts a full lameness exam.... Read More

Article

Neonatal Nuances

February 01, 2007

The first days of a foal's life can be risky; there are a number of things that can go wrong. Some problems can be dealt with easily (such as constipation), while others are life-threatening (such as a ruptured bladder).

In this article, Bonni... Read More

Article

Prevalence of PSSM in Quarter Horses

September 14, 2006

Up to 6% of apparently healthy Quarter Horses could have subclinical polysaccharide storage myopathy (PSSM).... Read More

Article

Feeding to Prevent and Control Disease

August 01, 2006

Dietary management can work like magic for specific equine diseases.... Read More

Article

More Than Skin Deep?

April 01, 2006

It was two years ago--in April of 2004--that this magazine published the announcement that the Poco Bueno Quarter Horse sire line had been identified as carrying the recessive gene that causes hyperelastosis cutis (HC, also known as hereditary... Read More

Article

Understanding Congenital Stationary Night Blindness

March 27, 2006

Canadian researchers are investigating the cause of a condition found primarily in Appaloosas that prevents them from seeing in the dark. Congenital stationary night blindness (CSNB) is a hereditary, non-progressive condition for which there is... Read More

Article

Inheritance of RER in Thoroughbreds: One Affected Parent Required

January 01, 2006

Recurrent exertional rhabdomyolysis (RER, tying-up) causes affected Thoroughbreds to suffer recurring episodes of muscle cramping, stiffness, excessive sweating, and a reluctance to move after exercise. With no cure available, information on how... Read More

Article

Inheritance of RER in Thoroughbreds

November 21, 2005

Recurrent exertional rhabdomyolysis (RER) causes affected Thoroughbreds to suffer recurring episodes of muscle cramping, stiffness, excessive sweating, and a reluctance to move after exercise. With no cure available, information on how RER might... Read More

Article

Equine Genetic Disease: Who's At Risk?

October 01, 2005

Many DNA sequence variations are fine; they just give rise to the broad spectrum of colors, sizes, and other characteristics we see in the horse population. Some variations, however, cause problems. These might range from a genetic predisposition... Read More

Article

GBED Linked to Quarter Horse Bloodlines

March 29, 2005

Glycogen-branching enzyme disorder (GBED) has likely been a cause of neonatal mortality in Quarter Horses for decades, according to Stephanie Valberg, DVM, PhD, who gave an update on her research on the disorder at the recent conference of the... Read More

Article

AAEP Convention 2004 Wrap-Up: Medicine/Treatments

March 03, 2005

Equine Malignant Hyperthermia

We've all heard of people and animals that are "sensitive" to anesthesia. Monica Aleman, MVZ, PhD, Dipl. ACVIM, head of the neuromuscular disease lab at the University of California, Davis, reported on a... Read More

Article

Newborn Foals: Routine and Emergency Care

February 14, 2005

The best chance to improve the survival rate of a newborn foal, she said, is adequate advance disease prevention and planning. The disease prevention includes a comprehensive vaccination program, Zimmel told her listeners.... Read More

Article

HC/HERDA Research

February 13, 2005

In horses with HC, the skin separates between the deep and superficial dermis. There is no cure. A DNA test for carrier identification is not yet available, and therefore, managed breeding strategy is currently the only option for reducing the incide... Read More

Article

Medicinal Control of Tying-Up

December 01, 2004

Dantrolene sodium (Dantrium) is used to control exertional rhabdomyolysis (ER, also called tying-up) in horses. Diagnosis of ER is typically confirmed by a finding of increased serum creatine kinase (CK), which is often greater than 1,000 IU at... Read More

Article

Hyperkalemic Periodic Paralysis and Colic

September 01, 2004

I have a 4-year-old Quarter Horse gelding who is HYPP N/H positive. This horse is very gassy and tends to colic... Read More

Article

Good/Bad Effects of Antioxidants

July 01, 2004

In a society that is trying to slow the aging process, free radicals and antioxidants are terms that are regularly tossed around. One might not realize their importance in horses, but researchers continue to pursue the details of how and why the... Read More

Article

Fatal Genetic Quarter Horse Disease Identified

June 09, 2004

Glycogen branching enzyme deficiency in Quarter Horses might cause unexplained stillbirths/deaths of foals.... Read More