Drug Research Designed to Ease Detection Time Uncertainties

New research conducted by a consortium including the Queensland University of Technology (QUT) is set to provide more certainty around the sometimes dicey business of administering therapeutic drugs to horses. QUT Professor of Biosciences Martin Sillence, PhD, said the new research pinpointed the length of time it took for 18 of the most commonly used therapeutic drugs to work their way out of a horse's system.

"Because horses (in Australia) are prohibited from racing with any trace of drugs in their system, the administration of therapeutic drugs to horses in need of care has been risky business," Sillence said. "It's been all too easy to unwittingly be caught out with a winning horse on race day, that's subsequently found to have traces of a drug in its system.

"Most commonly this is from the administration of therapeutic drugs to help a horse overcome an illness or muscular condition, he continued."With no accurate schedule to indicate how long drugs take to work their way out of horses' systems, a fair amount of guesswork has always been involved. The new schedule should change all this."

He also said the research would set the scene for better healthcare of horses.

"In the absence of certainty around drug excretion times, some trainers may have at times been reluctant to have horses treated and this has not always been in the horse's welfare," Sillence suggested."Now armed with more certainty, trainers and veterinarians can be more sure of the impact therapeutic drugs will have on horses and make better informed decisions about the best treatment regimes. It gives veterinarians and trainers the freedom to use legitimate medications with less risk of returning a positive drugs test."

Sillence said the research would provide the equine industry with the ability to set detection times with more confidence and accuracy and should result in fewer positive test returns: "It will provide the sport with greater integrity."

Sillence said each year the Australian horse industry had more than 650,000 starters in Thoroughbred and harness races and other equestrian pursuits. He added that the nation's Thoroughbred population was second only to that of the United States.

He said his research involved the examination of more than 20,000 blood and urine samples as well as the development of new forensic tests: "This work will now be shared internationally, enabling Australia to contribute to the international standardization of drug testing protocols."

The $1.2M four-year research project was funded by the Rural Industries Research and Development Corporation (RIRDC) and industry partners and was undertaken by the four Australian racing laboratories in Queensland, New South Wales, Western Australia, and Victoria together with QUT, Charles Sturt University, and the Universities of Queensland and Pennsylvania.

The full-length report, "The Pharmacokinetics of Equine Medications," is available from the RIRDC.

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