Researchers Explore Treating Arthritis at Molecular Level

Researchers are examining a promising genetic lab approach to curing osteoarthritis (OA) in horses.
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"Go small or go home" might be the new catch phrase at the Ohio State University’s Comparative Orthopedic Laboratory, where researchers are examining a novel molecular approach to finding the cure for osteoarthritis (OA) in horses. The team recently completed a study using this molecular approach, and the preliminary results they obtained were quite promising.

"Osteoarthritis remains a major problem in horses," explained Alicia L. Bertone, DVM, PhD, Dipl. ACVS, the Trueman Family Endowed Chair and Professor in Equine Orthopedic Surgery at The Ohio State University College of Veterinary Medicine and author on the study. "To date, ways to regenerate cartilage rather than simply reduce inflammation and control pain in affected horses remain to be discovered."

Nutritional supplements and regenerative therapies (such as stem cells and platelet-rich plasma) are currently available and are increasingly popular options for treating OA’s clinical signs; however, neither option has "proven" itself via an evidence-based medicine approach.

An alternative method of treating OA is to address the problem at the genetic level, and this was the approach examined by the researchers on the current study

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Written by:

Stacey Oke, MSc, DVM, is a practicing veterinarian and freelance medical writer and editor. She is interested in both large and small animals, as well as complementary and alternative medicine. Since 2005, she’s worked as a research consultant for nutritional supplement companies, assisted physicians and veterinarians in publishing research articles and textbooks, and written for a number of educational magazines and websites.

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