Cushing's Disease

Article

Remember Seasonal Variation in Cushing's Testing

October 22, 2009

Keep season in mind when testing for Cushing's disease (pituitary pars intermedia dysfunction, or PPID).... Read More

Article

Insulin Resistance: Variation in Blood Test Levels

October 14, 2009

A blood sample is usually a key step in diagnosing a horse as insulin resistant. But a recent study showed that one sample might not give enough information for an accurate diagnosis, because the horse's blood sugar and insulin fluctuates daily. ... Read More

Article

TheHorse.com en Español: El Otoño Trae Desafío Para el Diagnóstico y Manejo de la Enfermedad de Cushing

October 13, 2009

This is one of a series of articles translated as part of our partnership with A Caballo, an equine publication based in Mexico, and Jorge Murga, DVM. Keep an eye on... Read More

Article

TheHorse.com en Español: AAEP 2008 Causas de Laminitis

October 07, 2009

This is one of a series of articles translated as part of our partnership with A Caballo, an equine publication based in Mexico, and Jorge Murga, DVM. Keep an... Read More

Article

Aged Horse Health Screenings Recommended, ACVIM 2009

July 24, 2009

Lameness, weight loss, colic, and equine Cushing's syndrome are the four top reasons for euthanizing an older horse, said Catherine McGowan, BVSc, PhD, RCVS, European specialist in equine internal medicine, who presented research by Thomas... Read More

Article

Metformin a Therapy in Progress for Equine Insulin Resistance

May 25, 2009

Oregon State Researchers suggest that a low bioavailability and a rapid rate of elimination of the drug metformin might explain the "varied reports of clinical success" for improving insulin sensitivity in horses.

Metformin is an oral... Read More

Article

Auburn Researchers Need More Horses for Cushing's Study

May 18, 2009

Researchers at Auburn University still need horses to participate in a study that will examine the use of chasteberry (vitex agnus castus) supplements in horses with Cushing's disease.

Chasteberry supplements are ofte... Read More

Article

Cushing's or Metabolic Syndrome?

April 17, 2009

A horse with equine metabolic syndrome (EMS) is typically middle-aged with either generalized or regional adiposity (fat deposits). The horse with Cushing's or pituitary pars intermedia dysfunction (PPID) is typically older than the horse with EMS;... Read More

Article

Geldings Sought for Cushing's Study at Auburn

April 14, 2009

Researchers at Auburn University need horses to participate in a study that will examine the use of chasteberry (vitex agnus castus) supplements in horses with Cushing's disease.

This study, which is being conducted throug... Read More

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Internal Medicine Table Topic

March 17, 2009

Table topics from the 2008 AAEP Convention included internal medicine. ... Read More

Article

Stability and Efficacy of Compounded Pergolide Examined

February 21, 2009

Researchers have recently cautioned horse owners currently treating horses diagnosed with pituitary pars intermedia dysfunction (PPID, or equine Cushing's syndrome) that the compounded form of the drug pergolide mesylate can become... Read More

Article

Glucosamine in a Cushing's Horse?

December 01, 2008

Q: As soon as my 20-year-old gelding was diagnosed with equine Cushing's disease, I eliminated glucosamine from his diet. However, he appears to have become gradually and increasingly stiff and short-strided without it. I really think that it helped ... Read More

Article

Cushing's Horses Sought for Pergolide Study

November 25, 2008

Elanco Animal Health (a division of Eli Lilly and Company), in collaboration with Michigan State University, Oklahoma State University, and Louisiana State University, is seeking horses with equine Cushing's disease, also known as pituitary pars... Read More

Article

Autumn Challenges for Cushing's Diagnosis, Management

September 27, 2008

Owners of older horses that exhibit any of the classic signs of Cushing's during the fall months work with their veterinarians to determine whether they should test or treat horses until diagnoses can be confirmed.... Read More

Article

Diagnosing Insulin Resistance: Q&A with Researchers

August 28, 2008

Over the past few years researchers have described a strong association between insulin resistance and laminitis in equines. They are working now on defining standard testing protocols and interpretations to identify horses at highest risk for... Read More

Article

Laminitis, PPID: The Science of Seasons Behind Them

July 20, 2008

Research groups reported their findings of the impact of seasonal variations for pituitary glad dysfunction.... Read More

Video

Metabolic Disorders

July 10, 2008

... Read More

Article

Cushing's, Parkinson's Link? Oklahoma State Researcher Receives Grant for Study

December 10, 2007

Dianne McFarlane, DVM, PhD, Dipl. ACVIM, Dipl. ABVP, is an assistant professor with the Oklahoma State University (OSU) Center for Veterinary Health Sciences. McFarlane recently received a grant from the National Institutes of Health (NIH) to... Read More

Article

Wedgewood Introduces Peppermint- and Alfalfa-Flavored Pergolide

December 04, 2007

Wedgewood Pharmacy has introduced peppermint- and alfalfa-flavored pergolide for horses in its Gourmeds dosage form. Gourmeds are chewable, naturally flavored tablets that are easy to administer.

Pergolide mesylate, a drug used to treat... Read More

Article

Carb Testing Program for Horse Feed and Hay

October 30, 2007

When it comes to horses, what does "low carb" mean? Lower than what? "There are several analytical procedures that measure sugar, and each one measures a slightly different fraction," said Kathryn Watts, BS, owner of Rocky Mountain Research & Consult... Read More

Article

Healthy Horses: Endocrine System Function and Flaws

September 25, 2007

Horses suffer from few endocrine disorders compared to humans and companion animals; however, they're not totally off the hook, explained Emily Graves, VMD, MS, Dipl. ACVIM, of Michigan State University, to horse owners in attendance at the... Read More

Article

What Causes Pituitary Pars Intermedia Dysfunction?

July 23, 2007

The lack of dopamine is critical, as the activity of the pars intermedia is normally inhibited (controlled) by dopamine. Without dopamine, the pars intermedia produces much more hormone than it should, causing the clinical signs of PPID.... Read More

Article

Treating Pituitary Pars Intermedia Dysfunction (or Cushing's Disease)

July 19, 2007

Medication options for PPID include pergolide, cyproheptadine, trilostane, and chasteberry extract. One disadvantage is that no treatment is currently FDA-approved for PPID in horses.... Read More

Article

Understanding Pituitary Pars Intermedia Dysfunction (a.k.a. Cushing's Disease)

July 18, 2007

Pituitary pars intermedia dysfunction--PPID, or Cushing's disease--is the most common disease of horses and ponies 15 years of age or older. Although it's not fully understood yet, researchers are learning more about how to treat and prevent it.... Read More

Article

Diagnosing Pituitary Pars Intermedia Dysfunction

July 17, 2007

Unfortunately, no perfect PPID test (one that is 100% accurate with a single-sample test) yet exists. At the 2006 AAEP Convention, Harold Schott, DVM, PhD, Dipl. ACVIM, professor of large animal clinical sciences at Michigan State University,... Read More