Top Reasons for Early Embryonic Death Described (AAEP 2012)

One veterinarian says many cases of early embryonic death (EED) are probably not preventable.
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Pregnancy loss in the early days of gestation perplex veterinarians and owners perpetually; after taking every measure to protect the embryo visible at Day 15 after ovulation, mares sometimes come up empty. And while scientists have learned volumes about getting mares in foal, there’s plenty left to decipher when it comes to keeping them there in the early days of conceptus life.

Tom Stout, VetMB, PhD, of the Department of Equine Sciences at Utrecht University, in The Netherlands, observed, “We have achieved impressive improvements in per-cycle and per-season pregnancy rates in well-managed horse farms over the past 20 years. (However,) our knowledge of factors contributing to the loss of 15% of the pregnancies detected at Day 15 after ovulation is lagging.”

The majority of pregnancies, more than 60% in fact, are lost by Day 42 after ovulation.

Scientists know little about the reasons for early embryonic death (EED) and to what extent they can prevent it. Although they generally believe a “progesterone insufficiency” is the underlying cause of EED. At the 2012 American Association of Equine Practitioners’ Convention, held Dec. 1-5 in Anaheim, Calif., Stout indicated that progesterone insufficiency is not often (or always) the cause of EED

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Written by:

Stacey Oke, MSc, DVM, is a practicing veterinarian and freelance medical writer and editor. She is interested in both large and small animals, as well as complementary and alternative medicine. Since 2005, she’s worked as a research consultant for nutritional supplement companies, assisted physicians and veterinarians in publishing research articles and textbooks, and written for a number of educational magazines and websites.

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