Endotoxemia

Article

Show Jumper Presley Boy in Intensive Care with Laminitis

July 16, 2012

The stallion worked July 5 before developing colic and endotoxemia that night. He remains in intensive care.... Read More

Article

Endotoxemia Explained

November 01, 2011

Endotoxin release--which happens when the bowel's checks and balances are altered--causes serious issues.... Read More

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Equine Gastrointestinal Tract/Ulcers

March 08, 2010

A summary of presentations on the equine gastrointestinal tract and ulcers at the 2009 AAEP Convention.... Read More

Article

DMSO Doesn't Help Gastric Aspects of Endotoxemia, AAEP 2009

January 22, 2010

Endotoxemia causes delayed gastric (stomach) emptying, which can cause the stomach to retain acidic contents and cause or worsen gastric ulcers. At worst, delayed gastric emptying can lead to accumulation of reflux material and gastric rupture.... Read More

Article

Experimental Endotoxemia Drug Performs Poorly in Horse Study

August 23, 2009

Pirfenidone, a unique experimental drug with anti-fibrotic and anti-inflammatory properties, afforded no apparent therapeutic benefit in horses with experimentally-induced endotoxemia, leaving Cal Davis researchers rather disappointed.... Read More

Article

ACVIM Conference Highlights

October 01, 2008

Among the hot topics this year were nutritional supplements, infectious disease, and metabolism problems.

What do nutritional supplements, infectious diseases, and snake bites have in common? All were considered "hot... Read More

Article

Experimental Drug Research Provides Promising Results

July 24, 2008

Endotoxemia. Septic shock. Intestinal ischemia. What do all these ailments have in common? Based on recent studies, some researchers think an investigational drug called pirfenidone might be a treatment option for all three.

"Pirfenidone,... Read More

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Colic and Digestive Health

March 23, 2007

Equine experts at the 2006 AAEP Convention discussed the research, risks, evaluation, & treatments for colic.... Read More

Article

Small Volume Resuscitation in Anesthetized Endotoxemic Horses

September 14, 2006

Endotoxemia occurs when toxins from the wall of Gram-negative bacteria crosses the intestinal wall and gains access to the bloodstream. Endotoxin becomes concentrated on the surface of white blood cells, causing them to secrete inflammatory agents. ... Read More

Article

Endurance and Endotoxemia

July 01, 2004

Endotoxemia in horses is usually associated with severe infections, inflammation, and colic. Endotoxin from intestinal bacteria activates release of inflammatory mediators such as thromboxane B2 (TxB2), tumor necrosis factor-alpha (TNF-alpha),... Read More

Article

New Treatment for Endotoxemia

March 01, 2003

Michelle Henry Barton, DVM, PhD, of the University of Georgia, recently completed a project on treating endotoxemia with polymyxin B (PMB), an alternative to endotoxin antibody products. The drug PMB kills many Gram-negative bacteria and also... Read More

Article

Endotoxemia and Gastrointestinal Disease

February 01, 2002

Endotoxemia is one of the most commonly encountered life-threatening conditions in horses with gastrointestinal disease. It is, by nature, a very disappointing and frustrating disease to encounter, and is the leading cause of death in adult horses... Read More

Article

"Glass Horse" Unveiled at Veterinary Convention

January 03, 2002

Hundreds of veterinarians waited patiently in line in San Diego, Calif., on the afternoon of Nov. 26—and not at the airport. They were waiting in the American Association of Equine Practitioners convention trade show to purchase a copy of “The... Read More

Article

AAEP 1995 Convention Roundup

October 04, 2001

A total of 2,351 equine veterinarians--a record attendance--descended on Lexington for the 41st annual American Association of Equine Practitioners convention. Committee business dominated the day on Dec. 2, with 21 of the association's 40... Read More