Cushing's Disease

Article

Challenges of Cushing's Disease Diagnosis and Treatment

July 02, 2007

We know Cushing's disease (or pituitary pars intermedia dysfunction—PPID—as it's more scientifically called), simply put, is an "old-horse disease" that results in metabolism disturbances and an abnormally heavy hair coat. But when it comes to... Read More

Article

Pergolide: FDA to Allow Compounding From Bulk

May 11, 2007

The Food and Drug Administration's (FDA) Center for Veterinary Medicine announced on May 11 it will allow bulk pergolide to be used in compounding pergolide for use in horses.

Pergolide mesylate, a drug commonly used to treat pituitar... Read More

Article

Pergolide Availability: No FDA Announcement, Supplies Running Low

May 04, 2007

More than a month after pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, was withdrawn for human use, the FDA has yet to make an announcement on whether... Read More

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Pergolide: Veterinarians, Horse Owners Fighting for Availability

April 17, 2007

Pergolide mesylate, a drug commonly used to treat pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, has been withdrawn for human use. The FDA made this announcement March 29. Since that time, horse owners and... Read More

Article

Equine Cushing's Drug Pergolide to be Withdrawn for Human Use

April 04, 2007

The FDA has announced pergolide is to be voluntarily withdrawn for human use. Pergolide is commonly used for horses with pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease.

According to the FDA announcement... Read More

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Obese Horses

March 23, 2007

Experts at the 2006 AAEP Convention discussed equine obesity in depth.... Read More

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Horse Management and Care

March 23, 2007

Management topics at the 2006 AAEP Convention included numerous tips for keeping older horses healthy.... Read More

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AAEP Convention 2006: Obese Horses

March 01, 2007

Adipobiology (The Study of Fat in the Body): An Emerging Field... Read More

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Nutrition to Go

March 01, 2007

A group of veterinarians gathered at the Land O' Lakes Purina Mills headquarters in St. Louis, Mo., last fall to participate in discussions on subjects that ranged from Cushing's disease to proper nutrition for horses young and old. Nicholas Frank,... Read More

Article

Equine Metabolic Syndrome Versus Cushing's Syndrome

February 19, 2007

Fresh from the AAEP Annual Convention, here's an update on what we know about these two disorders and how to manage them:

Equine metabolic syndrome typically affects horses aged 8 to 18-years-old. Pony breeds, domesticated Spanish... Read More

Article

Dopamine and Its Evil Twin Ergovaline

February 01, 2007

In the horse, the hormone dopamine exerts a number of effects through its actions on the pituitary gland. Both dopamine and ergovaline, a dopaminergic agonist (a drug that stimulates dopamine receptors), can significantly impact the mare's... Read More

Article

Cushing's Disease in Horses

March 01, 2006

It's spring, yet your aging equine has failed to shed his long, shaggy, winter coat. Furthermore, he's developed a saggy belly coupled with loss of muscle over his croup and rump. He's gulping down far more water than he used to, and his stall i... Read More

Article

AAEP Convention 2004 Wrap-Up: Horseman's Day

March 03, 2005

Horseman's Day, as part of the annual American Association of Equine Practitioners Convention, just keeps getting better and better. And attendance is strong no matter where the convention is held. Most recently, the locale was Denver, Colo., on... Read More

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AAEP Convention 2004 Wrap-Up: Medicine/Treatments

March 03, 2005

Equine Malignant Hyperthermia

We've all heard of people and animals that are "sensitive" to anesthesia. Monica Aleman, MVZ, PhD, Dipl. ACVIM, head of the neuromuscular disease lab at the University of California, Davis, reported on a... Read More

Article

Thyroid/Cushing's Disease

February 14, 2005

Quite often, she said, horses suffering from laminitis, obesity, and poor fertility are administered thyroid hormone supplementation. But in many of these cases proper documentation or accurate diagnosis of hypothyroidism is non-existent.... Read More

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AAEP Convention 2004: Horseman's Day--Cushings

February 14, 2005

Christy Malazdrewich, DVM, MVSc, PhD, Dipl. ACVIM, assistant clinical professor at the University of Minnesota, discussed metabolic problems at Horseman's Day at the 50th annual American Association of Equine Practitioners (AAEP) Convention in... Read More

Article

Don't Bypass a Veterinarian

November 01, 2004

I have an older Tennessee Walking Horse with Cushing's disease. She has been on Cipro for some time. She foundered long before I got her, but it has become chronic. I have been able to maintain her to a point, but she is losing weight and I have a... Read More

Article

Feeding the Cushingoid Horse

October 01, 2004

Can you provide more information on feeding the Cushing's horse? My dressage horse has Cushing's and is on cyproheptadine and Thyro-L, grass hay, and a quarter-cup of 10% sweet feed. I am worried he is not getting the essential... Read More

Article

Equine Metabolic Syndrome

October 01, 2004

Equine metabolic syndrome (EMS), Cushing's disease, insulin resistance (IR), glucose intolerance, and glycemic indices of feeds have gotten a lot of press lately. The terms are taken from the human literature, where they have very specific... Read More

Article

New Method of Counting Carbs

August 19, 2004

A new carbohydrate analysis method developed for the National Aeronautics and Space Administration (NASA) might be able to help researchers answer some specific questions about equine forages. Until now, it has been difficult for forage... Read More

Article

Trilostane for Cushing's Disease

June 01, 2004

Equine Cushing's syndrome (ECS), or hyperadrenocorticism, is caused by an excess of cortisol. This syndrome produces signs including excessive hair growth (hirsutism), lethargy, fat redistribution under the skin, chronic/relapsing laminitis, and... Read More

Article

Obesity and Cushing's Disease

April 01, 2004

There is speculation that metabolic syndrome could be a factor in horses which develop Cushing's disease. ... Read More

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Diet: When Horses Need Less Carbs

April 01, 2004

Research suggests some horses (growing foals, laminitic horses, etc.) could do well on low-glycemic diets. ... Read More

Article

Cushing's Disease and Laminitis--Not Just Old Horses

April 01, 2004

Researchers recently revealed that Cushing's disease is a major contributing factor to laminitis among horses in a primary care veterinary practice, and that the median age of laminitic Cushing's horses was 15 1/2 years--disproving tha... Read More

Article

Equine Metabolic Syndrome and Laminitis

May 01, 2003

Of particular interest to horse owners was Johnson's black-and-white linkage of the newly termed EMS condition with laminitis and obesity. "Obesity-associated insulin refractory state" was Johnson's precise description of "Equine Metabolic Syndrome" ... Read More