Prolonged Use of Bute Detrimental to Joint Cartilage

Chronic use of phenylbutazone, or Bute, in horses with joint problems could be causing more problems than it’s preventing. A recent study has shown that Bute and other non-steroidal anti-inflammatory medications (NSAIDS) might be detrimental to joint cartilage regeneration in horses.

The study was performed by Lisa Beluche, DVM; Alicia Bertone, DVM, PhD, Dipl. ACVS; David Anderson,

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Chronic use of phenylbutazone, or Bute, in horses with joint problems could be causing more problems than it’s preventing. A recent study has shown that Bute and other non-steroidal anti-inflammatory medications (NSAIDS) might be detrimental to joint cartilage regeneration in horses.

The study was performed by Lisa Beluche, DVM; Alicia Bertone, DVM, PhD, Dipl. ACVS; David Anderson, DVM; and Carsten Rohde, DVM; of The Ohio State University’s (OSU) Orthopedic Research Laboratory, and appeared in a recent issue of the American Journal of Veterinary Research. Eleven sound and radiographically normal 18- to 30-month-old horses were used in the study

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Written by:

Stephanie L. Church, Editorial Director, grew up riding and caring for her family’s horses in Central Virginia and received a B.A. in journalism and equestrian studies from Averett University. She joined The Horse in 1999 and has led the editorial team since 2010. A 4-H and Pony Club graduate, she enjoys dressage, eventing, and trail riding with her former graded-stakes-winning Thoroughbred gelding, It Happened Again (“Happy”). Stephanie and Happy are based in Lexington, Kentucky.

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