Equine Protozoal Myeloencephalitis (EPM)
- By Stacey Oke, DVM, MSc
- Nov 08, 2012
Equine protozoal myeloencephalitis (EPM) is a progressive and potentially fatal neurologic disease in horses caused by protozoal (single cell) microorganism, most commonly Sarcocystis neurona, which causes inflammation in the brain and/or spinal cord.
Opossums, the primary intermediate host in the life cycle of S. neurona, excrete parasite oocysts (akin to an egg) in their feces, which subsequently develop into sporocysts (infective spores). Horses become inadvertently infected when they ingest the sporocysts while grazing.
Clinical signs of EPM are usually asymmetrical (worse on one side of the body). Signs can be as mild as a slight decrease in performance or as severe as narcolepsy, seizuring, and collapse.
- Relationship between S. neurona and EPM Examined
- Equine Protozoal Myeloencephalitis: Past and Present
- What's New With Equine Protozoal Myeloencephalitis?
- EPM Incidence in Horses: Holding Steady (AAEP 2010)
- Indistinct Gait Deficits: Musculoskeletal and Neurologic Causes
- EPM Diagnosis and Treatment Recommendations
- Horse Sleep Disorders and Seizures Reviewed for Equine Vets
- EPM: Is DMSO the Cure for Treatment Issues?
- Equine Protozoal Myeloencephalitis (EPM): Debunking the Myths
- Vets Discuss Infectious Neurologic Diseases, AAEP 2008