Equine Protozoal Myeloencephalitis (EPM)


Spinal Taps Unnecessary for EPM Diagnosis?

July 07, 2006

While cerebrospinal fluid (CSF) testing for equine protozoal myloencephalitis (EPM) is widely regarded as the only definitive way to diagnose the disease, the difficult, expensive, and potentially dangerous test might not be necessary, according... Read More


Recovering From EPM

July 01, 2006

My horse was diagnosed about six months ago with EPM. Can I help him gain his strength back in his hind legs?... Read More


Neurologic Case Shows Difficulty of Rule-Outs

April 01, 2006

A 24-year-old pleasure mare in Brunswick, Ga., has been diagnosed with concurrent infections of equine protozoal myeloencephalitis (EPM) and equine herpesvirus type-1 (EHV-1). Both can cause neurologic disease.

This case highlights the... Read More


Georgia Neurologic Case Highlights Difficulty of Rule-Outs

February 23, 2006

A 24-year-old pleasure mare in Brunswick, Ga., was recently diagnosed with concurrent infections of equine protozoal myeloencephalitis (EPM) and equine herpesvirus type-1 (EHV-1), both of which can cause clinical signs of neurologic disease... Read More


AAEP Convention 2005: Infectious Neurologic Disease

February 17, 2006

Sometimes subtle and often dramatic, infectious neurologic disease cases are things veterinarians never want to see, although most would like to understand them better and more easily recognize them when they appear in clients' horses. From... Read More


AAEP Convention 2005: Early Diagnosis of EPM with Biomarkers

February 16, 2006

A researcher has found a reliable way to diagnose equine protozoal myeloencephalitis (EPM) in the acutely affected horse by examining genetic markers in its blood. This technique could potentially be applied to detect evidence of other infectiou... Read More


EPM Check-Up

February 01, 2006

Although progress has been made studying equine protozoal myeloencephalitis (EPM) in the last 10 years, some aspects of the disease remain elusive. One researcher, half-jokingly, notes that EPM is considered the most diagnosed neurologic disorde... Read More


No Rotation Deworming (Excerpt)

November 02, 2005

Programs that use no rotation involve the continued use of one effective drug until it no longer reduces small strongyle numbers as indicated by fecal egg counts. The intervals of administration depend on the dewormer used, but this program is limite... Read More


EPM: Not So Common?

May 01, 2005

"Equine protozoal myeloencephalitis (EPM) is a common cause of neurological disease of horses in North and South America, and results from a protozoal infection with Sarcocystis neurona or Neospora hughesi (less commonly)," said... Read More


Twelve Years of EPM Research: Are We Any Smarter?

April 25, 2005

"I think every time we find out something about EPM (equine protozoal myeloencephalitis), it turns up more questions," said Bill Saville, DVM, PhD, Dipl. ACVIM, an associate professor in the Department of Veterinary Preventive Medicine at The... Read More


Equine Protozoal Myeloencephalitis: Less Common Than We Thought?

March 22, 2005

"Equine protozoal myeloencephalitis (EPM) is a common cause of neurological disease of horses in North and South America, and results from a protozoal infection with Sarcocystis neurona or Neospora hughesi (less commonly),"... Read More


EPM Parasite Isolated from Healthy Horse's Blood

March 02, 2005

Scientists recently isolated the parasite that causes the neurological disease equine protozoal myeloencephalitis (EPM) from the blood of an immunocompetent horse--a normal, healthy horse. This research could lead to a better understanding of th... Read More


EPM: Still an Enigma or Under Control?

August 01, 2004

Dynamic discussions about future equine protozoal myeloencephalitis (EPM) diagnostic methods and current EPM treatments were sparked at a June 11 meeting of the Equine Protozoal Myeloencephalitis Society (EPMS) in Minneapolis, Minn. The event,... Read More


Neurologic Conditions, In-Depth

March 02, 2004

Assessing neurologic conditions might seem difficult, but with practice and attention to the subtle differences between different conditions' deficits, the process can become easier. Additionally, practitioners discussed vaccination and treatment opt... Read More


Neurologic Disease Discussed

March 01, 2004

Morgan stressed that good management practices can reduce the risk factors that contribute to neurologic disease incidence. Keep feed sources clean and free of opossums and protect your hay from rodent infestation.... Read More


What is EPM?

February 03, 2004

EPM is a protozoal disease that causes inflammation in the brain and spinal cord of the horse. In the late 1970s to early 1980s, Morgan said there was debate whether a toxoplasma or Sarcocystis organism was the cause. ... Read More


New EPM Treatment Approved

January 01, 2004

On Nov. 19 the U.S. Food and Drug Administration (FDA) approved Navigator for treating equine protozoal myeloencephalitis (EPM). This drug has been under development for more than six years.

IDEXX Laboratories of Westbrook, Maine, received... Read More


More on the New EPM Treatment

December 03, 2003

(Revised 12/5/03) Horse owners have a new option for treating equine protozoal myeloencephalitis (EPM) following the Nov. 19 U.S. Food and Drug Administration's (FDA) approval of nitazoxanide. This medication has been under development... Read More


FDA Approves New EPM Treatment

November 20, 2003

IDEXX Laboratories, Inc. announced Nov. 19 that it received approval from the U.S. Food and Drug Administration (FDA) to market and sell Navigator (32% nitazoxanide) antiprotozoal oral paste, a new treatment for equine protozoal myeloencephaliti... Read More


Folic Acid Supplementation

November 01, 2003

Sulphadiazine and pyrimethamine are used in combination to treat equine protozoal myeloencephalitis (EPM). These drugs interfere with folic acid (folate) metabolism, a vitamin essential for survival of the causative protozoon Sarcocystis... Read More


Dealing With EPM Today

September 01, 2003

While West Nile virus continues to dominate headlines when it comes to equine health, researchers are working to unlock the mysteries of that other, not-quite-so-new disease--equine protozoal myeloencephalitis (EPM). High on the list is... Read More


The Latest on EPM Research

September 01, 2003

The annual American Association of Veterinary Parasitologists met July 19-22 with presentations on many equine-related topics. The EPM Society held a roundtable during that meeting after presentations from top EPM (equine protozoal... Read More


The Latest on EPM

July 23, 2003

Is it possible that the horse is a natural intermediate host in the life cycle of the parasite that causes equine protozoal myeloencephalitis (EPM), meaning the parasite can develop to a reproductive state in the horse? Are there other parasites... Read More


EPM Testing in Foals

July 01, 2003

Diagnosis of equine protozoal myeloencephalitis (EPM) involves a technique called Western blotting (WB), which identifies antibodies against Sarcocystis neurona, the parasite responsible for the disease. A positive result on WB does not... Read More


Preventing EPM

March 01, 2003

Saville presented a summary of what is known about EPM, and he believes that with better understanding of the disease, wildlife management, risk-factor manipulation, prophylactic medications, and possible vaccination, that prevention of EPM can be at... Read More