Equine Protozoal Myeloencephalitis (EPM)


Research Efforts Focus on EPM Prevention

January 18, 2009

Equine protozoal myeloencephalitis (EPM) is an infection of the brain and spinal cord of horses by single-celled parasites known as protozoa. EPM, which is the most commonly diagnosed neurological disorder in horses, can be a permanently... Read More


Opossum Patrol: Readers Share Control Strategies

November 17, 2008

Nearly 900 readers of TheHorse.com responded to a poll asking, "Do you take any steps to limit opossums around your farm to reduce the chance your horses will get EPM?"

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Neurology to be Focus of AAEP State-of-the-Art Lecture

June 30, 2008

Stephen M. Reed, DVM, Dipl. ACVIM, will deliver the Frank J. Milne State-of-the-Art Lecture on Dec. 8 during the American Association of Equine Practitioners' 54th Annual Convention in San Diego, Calif. Equine neurology is the focus of this year's... Read More


Ponazuril and EPM: An Ounce of Prevention

April 25, 2008

Researchers at the University of Florida studying equine protozoal myeloencephalitis (EPM) recently found that administering ponazuril once every seven days might prevent EPM caused by Sarcocystis neurona.

Equine protozoal... Read More


Vaccination Schedule Guidelines

April 21, 2008

Developing a vaccination schedule is not as straightforward as it sounds. So much of what you should vaccinate for depends upon such factors as where you live, how often your horse travels, how old he is, his vaccination history, and what infectious ... Read More


EPM Treatment

April 01, 2008

To understand the best approach to treating equine protozoal myeloencephalitis (EPM), it is helpful to have a brief look at how the protozoa (single-celled parasites) that cause EPM--Sarcocystis neurona--enter the central nervous system.... Read More


EPM Prevention

April 01, 2008

How can you keep your horses safe from EPM?

The best way to keep your horses healthy is prevent them from getting sick. Sounds absurdly simple, right? In theory, this works. But in the real world of trying to protect horse... Read More


EPM Diagnosis

April 01, 2008

Could EPM be causing your horse's performance to be just a little off? Equine protozoal myeloencephalitis (EPM) continues to be an elusive disease to prevent, diagnose, and treat in horses. In this special collection of three articles... Read More


Ever-Elusive EPM

April 01, 2008

Charlie (not his real name) had been a patient at our clinic on several occasions. He was always gentle and cooperative as we tried to determine what was causing his curious collection of clinical signs. He had tolerated everything from the obvious... Read More


Today's EPM

April 01, 2008

What have we learned about equine protozoal myeloencephalitis (EPM) since it first was reported in 1995? A lot, and not enough. EPM has been called the "most overdiagnosed neurologic disease in the United States" by some researchers and... Read More


Readers Respond: Encountering EPM

January 31, 2008

More than 1,300 readers of TheHorse.com responded to a poll asking, "Have horses close to you experienced EPM?"

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New EPM Research Sheds Light on Spread of Causative Parasite

January 16, 2008

After years of studying equine protozoal myeloencephalitis (EPM), a serious neurological disease in horses, scientists have mapped the first steps in the migratory path of Sarcocystis neurona--the chief parasitic cause of EPM.

"Befor... Read More


Study Links New Risk Factors to EPM Infection

January 04, 2008

Results from a recent study on equine protozoal myeloencephalitis (EPM)--a progressive neurological disease--identified three factors that increase a horse's risk of infection: living with cats, use for Western performance or racing, and age... Read More


Shivers in the Horse: A Review

July 24, 2007

Shivers has been recognized by horse owners for more than a century and refers to a chronic nervous or neuromuscular condition that in a 1962 text was said to be "as common as dirt." This statement referred to the period when draft horse populations ... Read More


EPM Today: Testing and Treatments

June 01, 2007

Horses need to be serviceably sound and safe to ride to fulfill their functions. It is no wonder that equine protozoal myeloencephalitis (EPM) has been a dreaded disease ever since its rise to prominence in the 1990s, because horses with neurologic... Read More


Current Treatments for Equine Protozoal Myeloencephalitis

January 16, 2007

Equine Protozoal Myeloencephalitis (EPM) is one of the most common treatable neurological diseases of American horses and is caused by the apicomplexan protozoan Sarcocystis neurona. This protozoan penetrates the central nervous system,... Read More


"Tuesday Talk" Highlights Neurologic Issues

December 24, 2006

The Marion duPont Scott Equine Medical Center presented "Equine Neurological Issues Over the Life Course" during its first Tuesday Talk session of the season. The seminar, which was held in Leesburg, Virginia, on Tuesday, Dec. 5, featured Martin O.... Read More


Virginia Maryland Group Works at Solving the EPM Enigma

December 07, 2006

Researchers have puzzled over how Sarcocystis neurona, the single-celled protozoan parasite notorious for causing equine protozoal myeloencephalitis (EPM), travels from the intestine, through the blood-brain barrier, and into the centra... Read More


Lame or EPM?

November 01, 2006

About a year and a half ago, my horse was diagnosed with EPM, which he was treated for. Now he's having hock issues.... Read More


How S. Neurona Gets to the Horse's Central Nervous System

October 09, 2006

Scientists have shown the protozoan parasite that causes equine protozoal myeloencephalitis (EPM) might enter the horse's central nervous system hidden in leukocytes (white blood cells) that cross the blood-brain barrier.

"Horses are... Read More


Spinal Taps Not Necessary for EPM Testing?

August 01, 2006

Cerebrospinal fluid (CSF) testing for equine protozoal myeloencephalitis (EPM) has been widely regarded as the only definitive way to diagnose the disease. This test can be difficult, expensive, and potentially dangerous, and according to new... Read More


Spinal Taps Unnecessary for EPM Diagnosis?

July 07, 2006

While cerebrospinal fluid (CSF) testing for equine protozoal myloencephalitis (EPM) is widely regarded as the only definitive way to diagnose the disease, the difficult, expensive, and potentially dangerous test might not be necessary, according... Read More


Recovering From EPM

July 01, 2006

My horse was diagnosed about six months ago with EPM. Can I help him gain his strength back in his hind legs?... Read More


Neurologic Case Shows Difficulty of Rule-Outs

April 01, 2006

A 24-year-old pleasure mare in Brunswick, Ga., has been diagnosed with concurrent infections of equine protozoal myeloencephalitis (EPM) and equine herpesvirus type-1 (EHV-1). Both can cause neurologic disease.

This case highlights the... Read More


Georgia Neurologic Case Highlights Difficulty of Rule-Outs

February 23, 2006

A 24-year-old pleasure mare in Brunswick, Ga., was recently diagnosed with concurrent infections of equine protozoal myeloencephalitis (EPM) and equine herpesvirus type-1 (EHV-1), both of which can cause clinical signs of neurologic disease... Read More