USEF Rule Permits Use of Surpass

Effective Dec. 1, 2004, the United States Equestrian Federation (USEF) Equine Drugs and Medications Rule permits the therapeutic use of Surpass, a nonsteroidal anti-inflammatory product (NSAID) recently approved by the FDA for use in horses. Thi

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Effective Dec. 1, 2004, the United States Equestrian Federation (USEF) Equine Drugs and Medications Rule permits the therapeutic use of Surpass, a nonsteroidal anti-inflammatory product (NSAID) recently approved by the FDA for use in horses. This is a topical preparation of 1% diclofenac cream, from IDEXX Pharmaceuticals. (For more information on the FDA approval of Surpass, click here.)

The rule change, which was adopted by the Executive Committee on Nov. 16, establishes a quantitative restriction, i.e., maximum permitted plasma concentration, similar to those for other NSAIDs. USEF has also issued dose and time recommendations for this product, i.e., application recommendations, to help achieve compliance with the rule. The rule does not require a medication report to be filed in connection with the use of this product.

The application recommendations, which are consistent with IDEXX’s application instructions for Surpass, are as follows:

Every 12 hours, not more than 73 mg of diclofenac liposomal cream should be administered (not more than 146 mg per 24 hour period) to one affected site. This 73 mg dose equals a 5-inch ribbon of cream not greater than � inch width, which should be rubbed thoroughly into the hair over the joint or affected site using gloved hands. Administration of diclofenac cream should be discontinued 12 hours prior to competing. Do not apply diclofenac cream in combination with any other topical preparations including DMSO, nitrofurazone, or liniments, and do not use on an open wound. Diclofenac cream should not be administered for more than 10 successive days

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